Premium
A class of 2D graphical representations of RNA secondary structures and the analysis of similarity based on them
Author(s) -
Yao YuHua,
Nan XuYing,
Wang TianMing
Publication year - 2005
Publication title -
journal of computational chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.907
H-Index - 188
eISSN - 1096-987X
pISSN - 0192-8651
DOI - 10.1002/jcc.20271
Subject(s) - class (philosophy) , representation (politics) , set (abstract data type) , similarity (geometry) , rna , computer science , theoretical computer science , graphical display , nucleic acid , mathematics , algebra over a field , artificial intelligence , pure mathematics , biology , genetics , programming language , computer graphics (images) , politics , political science , law , image (mathematics) , gene
Based on the concepts of cell and system of graphical representation, a class of 2D graphical representations of RNA secondary structures are given in terms of classifications of bases of nucleic acids. The representations can completely avoid loss of information associated with crossing and overlapping of the corresponding curve. As an application, we make quantitative comparisons for a set of RNA secondary structures at the 3′‐terminus of different viruses based on the graphical representations. The examination of similarities/dissimilarities illustrates the utility of the approach. © 2005 Wiley Periodicals, Inc. J Comput Chem 26: 1339–1346, 2005