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Molecular Imaging and Oral Cancer Diagnosis and Therapy
Author(s) -
Keshavarzi Maryam,
Darijani Mansoreh,
Momeni Fatemeh,
Moradi Pouya,
Ebrahimnejad Hamed,
Masoudifar Aria,
Mirzaei Hamed
Publication year - 2017
Publication title -
journal of cellular biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 165
eISSN - 1097-4644
pISSN - 0730-2312
DOI - 10.1002/jcb.26042
Subject(s) - medicine , magnetic resonance imaging , positron emission tomography , cancer , stage (stratigraphy) , basal cell , disease , molecular imaging , oral cavity , radiology , pathology , biology , in vivo , paleontology , microbiology and biotechnology , orthodontics
Oral cancer is known as one of relatively common type of cancer worldwide. Despite the easy access of the oral cavity to examination, oral tumors are diagnosed in more advanced stages of the disease. Imaging techniques have been recently emerged as non‐invasive approaches to detect molecular and cellular changes in living cells and organisms. These techniques such as computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET) could help physicians to screen patients with oral tumors particularly oral squamous cell carcinoma (OSCC) in early stage of the disease. In this review, we discuss that early detection and diagnosis of oral tumors through using more robust and precise imaging techniques and a variety of cellular/molecular biomarkers not only could lead to more effective and less aggressive form of treatment for the disease but also could improve survival rates and lower treatment costs. J. Cell. Biochem. 118: 3055–3060, 2017. © 2017 Wiley Periodicals, Inc.