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Two‐dimensional protein crystals (S‐layers): Fundamentals and applications
Author(s) -
Sleytr Uwe B.,
Sára Margit,
Messner Paul,
Pum Dietmar
Publication year - 1994
Publication title -
journal of cellular biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 165
eISSN - 1097-4644
pISSN - 0730-2312
DOI - 10.1002/jcb.240560209
Subject(s) - materials science , protein crystallization , nanotechnology , crystallography , chemistry , physics , crystallization , thermodynamics
Two‐diminsional crystalline surface layers (S‐layers) composed of prtein or glucoprotein subunits are one of the most commonly observed prokaryotic cell envelope structures. lsolated S‐layer Subunits are endowed with the ability to assemble into monomolecular arrays in suspension, on surfaces or interface by an entropy‐driven process. S‐layer lattices are isoporous structures with functional groups located on the surface in an identical position and orientation. These characteristic featupes have alreadu led to applicatioinns of S‐layers as (1) ultrafilration membranes with well‐defiled mmlecular weight cut ‐ooffs and excellent antifouling characteristics, (2) immobilization matrices for functional molecules as required for affiviy and enzyme memberanes, affiniy micricarriers and biosensors, (3) conjugate vaaines, (4) carriers for Langmuir‐Blodgett films and reconstituted biological memberanes, and (5) patterning elements in molecular nanotechnology.