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The SIE, SRE, CRE, and FAP‐1 four intracellular signal pathways between stimulus and the expression of c‐fos promoter
Author(s) -
He Hong,
Ping Feiyun
Publication year - 2009
Publication title -
journal of cellular biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 165
eISSN - 1097-4644
pISSN - 0730-2312
DOI - 10.1002/jcb.22058
Subject(s) - c fos , immediate early gene , serum response element , signal pathway , intracellular , gene expression , microbiology and biotechnology , chemistry , response element , signal transduction , stimulus (psychology) , gene , biology , promoter , serum response factor , biochemistry , psychology , psychotherapist
c‐fos gene has a close relationship with the osteoblasts. Mechanical signal effect on osteoblasts would change the expression level of c‐fos. Authors introduce the signal pathways of four cis ‐response elements on the promoter of c‐fos, that is, CRE (cAMP responsive element), FAP‐1 (Fbs‐AP‐1 site), SRE (serum response element), and SIE (sis‐inducible element), as the regulatory mechanism for c‐fos gene expression following various stimuli. J. Cell. Biochem. 106: 764–768, 2009. © 2009 Wiley‐Liss, Inc.