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Molecular imaging: The application of small animal positron emission tomography
Author(s) -
Rowland Douglas J.,
Lewis Jason S.,
Welch Michael J.
Publication year - 2002
Publication title -
journal of cellular biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 165
eISSN - 1097-4644
pISSN - 0730-2312
DOI - 10.1002/jcb.10417
Subject(s) - positron emission tomography , molecular imaging , pet imaging , imaging technology , medical physics , preclinical imaging , animal model , nuclear medicine , medicine , radiology , biology , microbiology and biotechnology , in vivo
The extraordinary advances in genomic technologies over the last decade have led to the establishment of new animal models of disease. The use of molecular imaging techniques to examine these models, preferably with non‐destructive imaging procedures, such as those offered by positron emission tomography (PET), are especially valuable for the timely advancement of research. With the use of small animal PET imaging it is possible to follow individual subjects of a sample population over an extended time period by using highly specific molecular probes and radiopharmaceuticals. In this Prospect small animal PET imaging will be described, specifically focusing on the current technologies, its applications in molecular imaging and the logistics of performing small animal PET. J. Cell. Biochem. Suppl. 39: 110–115, 2002. © 2002 Wiley‐Liss, Inc.