Premium
Solid phase chemical technologies for combinatorial chemistry
Author(s) -
Balasubramanian Shankar
Publication year - 2001
Publication title -
journal of cellular biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 165
eISSN - 1097-4644
pISSN - 0730-2312
DOI - 10.1002/jcb.10063
Subject(s) - intramolecular force , chemistry , solid phase synthesis , combinatorial chemistry , stereoselectivity , cover (algebra) , biochemical engineering , organic chemistry , engineering , catalysis , biochemistry , mechanical engineering , peptide
This article describes the exploration of synthetic methodologies on solid phase for combinatorial chemistry. Examples will cover various cyclisation strategies that include; the intramolecular Heck cyclisation leading to the formation of oxindoles, the radical cyclisation mechanism in the synthesis of furans, and a stereoselective cyclisation to form oxopiperazines. J. Cell. Biochem. Suppl. 37: 28–33, 2001. © 2002 Wiley‐Liss, Inc.