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Optimization of parameters for maximization of plateletpheresis and lymphocytapheresis yields on the haemonetics model V50
Author(s) -
Aubuchon James P.,
Carter Charles S.,
Adde Melissa A.,
Meyer Donna R.,
Klein Harvey G.
Publication year - 1986
Publication title -
journal of clinical apheresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.697
H-Index - 46
eISSN - 1098-1101
pISSN - 0733-2459
DOI - 10.1002/jca.2920030205
Subject(s) - plateletpheresis , medicine , offset (computer science) , apheresis , surgery , platelet , immunology , computer science , programming language
Automated apheresis techniques afford the opportunity of tailoring collection parameters for each donor's hemato‐logic profile. This study investigated the effect of various settings of the volume offset parameter as utilized in the Haemonetics Model V50 instrumentation during platelet‐ and lymphocytapheresis to optimize product yield, purity, and collection efficiency. In both types of procedures, increased product yield could be obtained by using an increased volume offset for donors having lower hematocrits. This improvement was related to an increase in collection efficiency. Platelet products also contained fewer contaminating lymphocytes with this approach. Adjustment of the volume offset parameter can be utilized to make the most efficient use of donors and provide higher‐quality products.