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Acquired immunodeficiency syndrome (AIDS) ‐ apheresis and operative risks
Author(s) -
Kiprov Dobri D.,
Lippert Randolph,
Sandstrom Erik,
Jones Frank R.,
Cohen Richard J.,
Abrams Donald,
Busch David F.
Publication year - 1985
Publication title -
journal of clinical apheresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.697
H-Index - 46
eISSN - 1098-1101
pISSN - 0733-2459
DOI - 10.1002/jca.2920020436
Subject(s) - medicine , apheresis , plasmapheresis , immunology , disease , hepatitis , hemoperfusion , intensive care medicine , immunoadsorption , surgery , antibody , platelet , hemodialysis
The removal of immune complexes, autoantibodies and suppressor factors from the circulation of patients with AIDS and AIDS related conditions by plasmapheresis and selective immunoadsorption may play a role as a therapeutic modality in these disorders. Lymphocytapheresis may also be of potential use in AIDS related conditions with presumed autoimmune basis. Perfusion of plasma over immobilized protein A columns is being evaluated as a possible immunomodulatory and antitumor therapy in patients with AIDS related Kaposi's sarcoma. Although apheresis procedures as a therapeutic modality in AIDS related conditions are still at the experimental stage, preliminary results are encouraging. The possible transmission of the disease by blood products presents a health hazard to health workers involved in the field of apheresis. Since the mode of transmission of the disease appears to be similar to hepatitis B, strict hepatitis B precautions should be enforced in every case in which AIDS suspected blood is being processed.