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Putative methods for prevention and treatment of neonatal septicemia
Author(s) -
Christensen Robert D.
Publication year - 1984
Publication title -
journal of clinical apheresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.697
H-Index - 46
eISSN - 1098-1101
pISSN - 0733-2459
DOI - 10.1002/jca.2920020116
Subject(s) - medicine , sepsis , intensive care medicine , immunization , exchange transfusion , pediatrics , antimicrobial , immunology , antibody , microbiology and biotechnology , biology
The high mortality rate observed in newborn infants who contract bacterial sepsis within the first days of life has prompted investigators to seek new methods for the prevention and treatment of this disorder. Among the putative measures recommended for prevention are: (1) administration of antimicrobials to all infants at the time of delivery, (2) identification and treatment of pregnant women colonized with those bacteria known to be major neonatal pathogens and (3) immunization of women to major neonatal pathogens. Three other measures, targeted at diminishing the mortality and morbidity in those in whom preventive measures fail, include: (1) granulocyte transfusion, (2) exchange transfusion and (3) administration of antibody.