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Mononuclear cell collection using various techniques
Author(s) -
Dowling Regina,
Weber Virginia,
Osborne Louise,
Klein Harvey
Publication year - 1984
Publication title -
journal of clinical apheresis
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.697
H-Index - 46
eISSN - 1098-1101
pISSN - 0733-2459
DOI - 10.1002/jca.2920020108
Subject(s) - medicine , peripheral blood mononuclear cell , leukapheresis , apheresis , monocyte , lymphocyte , immunology , donation , in vitro , stem cell , biochemistry , chemistry , platelet , biology , cd34 , economics , genetics , economic growth
During the last 15 months, 609 mononuclear cell collections were performed. Lymphocytapheresis and monocytapheresis provides cells for in vitro research studies, investigational transfusion studies and as therapeutic procedures. Automated leukapheresis procedures yields from 1.0-1.5 X 10(9) lymphocytes per liter blood processed. Monocyte yields generally 1/10 of the lymphocyte yields in both lymphocytapheresis and monocytapheresis procedures. Donors had very few reactions, and post collection CBC's showed no significant abnormalities. Mononuclear cell donation appears to have no risk to the normal donor.