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The impact of delayed and immediate adverse events on the intention of future donations in whole blood and plateletpheresis donors
Author(s) -
Gupta Abhaykumar Malind,
Bajpai Meenu
Publication year - 2021
Publication title -
journal of clinical apheresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.697
H-Index - 46
eISSN - 1098-1101
pISSN - 0733-2459
DOI - 10.1002/jca.21902
Subject(s) - plateletpheresis , medicine , blood donor , adverse effect , surgery , platelet , immunology , apheresis
Abstract Background Adverse donor events (ADEs) are usually mild and short‐term with no sequelae, but may cause disinclination toward future donations. Aims To determine the impact of delayed ADEs (D‐ADEs) in addition to immediate ADEs (I‐ADEs) on the intention of future donations (IFDs) and to analyze the various associated factors. Methods ADEs were categorized following the ISBT working group on donor vigilance. Telephonic interviews of the donors were conducted 2 weeks after the whole blood (WB) and plateletpheresis donation to inquire about D‐ADEs and IFDs. Results A total of 3514 WB and 531 plateletpheresis donors were included in the study. WB donors had an overall higher IFD as compared to plateletpheresis donors (89.53% vs 57.06%, P < .001). A higher IFD was observed in male WB donors as compared to female WB donors (89.95% vs 75%, P < .001). Repeat WB donors had a higher IFD as compared with first‐time donors (93.66% vs 81.37%, P < .001). A total of 13.7% WB donors and 19.2% plateletpheresis donors reported D‐ADEs. WB donors who experienced D‐ADEs had a significantly lower IFD (78.38% vs 91.63%, P < .001) as compared with donors without any ADEs; a similar trend was observed in donors who experienced I‐ADEs (69.90% vs 91.63%, P < .001). In WB donors, systemic D‐ADEs such as fatigue had a more negative impact on IFDs as compared with localized D‐ADEs such as bruises (63.93% vs 86.83%, P < .001). Conclusions Both D‐ADEs and I‐ADEs negatively impact donors' intention to donate again. Systemic D‐ADEs had a more negative impact on IFDs as compared with localized D‐ADEs.