Premium
Autograft immune effector cells and survival in autologous peripheral blood hematopoietic stem cell transplantation
Author(s) -
Porrata Luis F.
Publication year - 2018
Publication title -
journal of clinical apheresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.697
H-Index - 46
eISSN - 1098-1101
pISSN - 0733-2459
DOI - 10.1002/jca.21611
Subject(s) - medicine , stem cell , haematopoiesis , immune system , peripheral blood stem cells , immunology , hematopoietic stem cell transplantation , transplantation , effector , hematopoietic stem cell , biology , microbiology and biotechnology
In addition to stem cells, T‐cells, natural killer cells, dendritic cells, and monocytes are also collected and infused from the autograft in patients undergoing autologous peripheral blood hematopoietic stem cell transplantation. Recent reports have shown that these autograft immune effector cells can affect the clinical outcome postautologous peripheral blood hematopoietic stem cell transplantation. In this article, I will review the clinical impact on the survival of these autograft immune effector cells conferring the concept of autologous graft versus tumor effect.