Severe intravenous immunoglobulin‐induced hemolysis with pigment nephropathy managed with red cell exchange | Zendy

Lasica Masa | Zendy; Zantomio Daniela | Zendy

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Severe intravenous immunoglobulin‐induced hemolysis with pigment nephropathy managed with red cell exchange

Author(s) -

Lasica Masa,

Zantomio Daniela

Publication year - 2016

Publication title -

journal of clinical apheresis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.697

H-Index - 46

eISSN - 1098-1101

pISSN - 0733-2459

DOI - 10.1002/jca.21416

Subject(s) - medicine , hemoglobinuria , hemolysis , apheresis , red cell , antibody , nephropathy , immunology , paroxysmal nocturnal hemoglobinuria , red blood cell , renal function , gastroenterology , platelet , endocrinology , diabetes mellitus

We report on the use of red cell exchange in a case of severe intravenous immune globulin induced hemolysis and pigment nephropathy. Renal impairment and hemoglobinuria were not ameliorated by supportive measures including hydration. Partial red cell exchange with group O blood reduced hemoglobinuria and appeared to stabilize renal function. This is the first report on the use of red cell exchange in this clinical setting. J. Clin. Apheresis 31:464–466, 2016. © 2015 Wiley Periodicals, Inc.

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