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Severe intravenous immunoglobulin‐induced hemolysis with pigment nephropathy managed with red cell exchange
Author(s) -
Lasica Masa,
Zantomio Daniela
Publication year - 2016
Publication title -
journal of clinical apheresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.697
H-Index - 46
eISSN - 1098-1101
pISSN - 0733-2459
DOI - 10.1002/jca.21416
Subject(s) - medicine , hemoglobinuria , hemolysis , apheresis , red cell , antibody , nephropathy , immunology , paroxysmal nocturnal hemoglobinuria , red blood cell , renal function , gastroenterology , platelet , endocrinology , diabetes mellitus
We report on the use of red cell exchange in a case of severe intravenous immune globulin induced hemolysis and pigment nephropathy. Renal impairment and hemoglobinuria were not ameliorated by supportive measures including hydration. Partial red cell exchange with group O blood reduced hemoglobinuria and appeared to stabilize renal function. This is the first report on the use of red cell exchange in this clinical setting. J. Clin. Apheresis 31:464–466, 2016. © 2015 Wiley Periodicals, Inc.