Premium
Therapeutic plasma exchange as a steroid‐sparing therapy in a patient with limbic encephalitis due to antibodies to voltage‐gated potassium channels
Author(s) -
Martin Isabella W.,
Martin ChristiLynn B.,
Dunbar Nancy M.,
Lee Stephen L.,
Szczepiorkowski Zbigniew M.
Publication year - 2016
Publication title -
journal of clinical apheresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.697
H-Index - 46
eISSN - 1098-1101
pISSN - 0733-2459
DOI - 10.1002/jca.21395
Subject(s) - limbic encephalitis , medicine , autoantibody , therapeutic plasma exchange , apheresis , plasmapheresis , antibody , immunology , platelet
Autoantibodies to the voltage‐gated potassium channel (VGKC) complex cause a spectrum of non‐paraneoplastic neurologic syndromes including limbic encephalitis (LE). We report a case of a man with LE who underwent a course of therapeutic plasma exchange (TPE) in addition to other immunomodulatory therapies and experienced sustained clinical resolution of his symptoms. This report adds to the existing literature supporting TPE in cases of LE due to VGKC complex autoantibodies. J. Clin. Apheresis 31:63–65, 2016. © 2015 Wiley Periodicals, Inc.