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Successful management of thrombotic thrombocytopenic purpura in a Jehovah's Witness without plasma exchange
Author(s) -
Chai Wanxing,
Chaudhry Abrar,
Rabinowitz Arthur P.
Publication year - 2015
Publication title -
journal of clinical apheresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.697
H-Index - 46
eISSN - 1098-1101
pISSN - 0733-2459
DOI - 10.1002/jca.21325
Subject(s) - thrombotic thrombocytopenic purpura , medicine , microangiopathic hemolytic anemia , apheresis , therapeutic plasma exchange , plasmapheresis , plateletpheresis , exchange transfusion , fresh frozen plasma , blood transfusion , purpura (gastropod) , thrombotic microangiopathy , platelet , surgery , immunology , antibody , disease , ecology , biology
Thrombotic thrombocytopenic purpura (TTP) is a hematologic emergency characterized by microangiopathic hemolytic anemia and thrombocytopenia. Plasma exchange is the standard treatment. Treating TTP without plasma exchange is a challenge. Due to religious beliefs, Jehovah's Witnesses do not accept transfusions of blood products. We report a case of successful treatment of TTP in a Jehovah's Witness using plasma exchange with albumin replacement. J. Clin. Apheresis 30:46–49, 2015. © 2014 Wiley Periodicals, Inc.