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The post‐platelet 100,000 count: Effects of platelet collection and future
Author(s) -
Jaben Elizabeth A.,
Gandhi Manish J.
Publication year - 2010
Publication title -
journal of clinical apheresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.697
H-Index - 46
eISSN - 1098-1101
pISSN - 0733-2459
DOI - 10.1002/jca.20270
Subject(s) - medicine , platelet , apheresis , plateletpheresis , food and drug administration , platelet transfusion , surgery , immunology , pharmacology
Currently, the majority of platelets transfused in the United States are collected by apheresis. The recent Food and Drug Administration guidance document published maintains that a postdonation platelet count for a donor remain >100,000/μL. During apheresis procedures, platelets are released from the splenic pool into circulation. This allows for higher postdonation platelet counts than anticipated. Some current plateletpheresis instruments take this into account when determining a safe product to be collected. On other instruments, the software does not allow for this correction. This may impact collections, but is expected to be resolved with a software update. J. Clin. Apheresis, 2011. © 2010 Wiley‐Liss, Inc.