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A case report of successful treatment with plasma exchange for adult‐onset Still's disease with autoimmune hepatitis
Author(s) -
Liu LinLin,
Feng MaoLing,
Wang LiNing,
Li XiaoLi,
Yao Li
Publication year - 2010
Publication title -
journal of clinical apheresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.697
H-Index - 46
eISSN - 1098-1101
pISSN - 0733-2459
DOI - 10.1002/jca.20227
Subject(s) - medicine , rash , adult onset still's disease , autoimmune hepatitis , sore throat , etiology , polyarthritis , pathogenesis , disease , immunology , hepatitis , dermatology , arthritis
Adult onset Still's disease (AOSD) is a rare systemic inflammatory disorder of unknown etiology and pathogenesis. The disease is characterized by typical spiking fever with evanescent rash, sore throat, polyarthralgias or polyarthritis, and involvement of various organs. Most of the reported cases with liver involvement occurred during the period of treatment with hepatotoxic drugs, whereas AOSD associated autoimmune hepatitis (AIH) is extremely rare. AIH may be an indicator of the poor prognosis of AOSD. Herein we describe a case of successful treatment with plasma exchange for AOSD‐associated AIH. J. Clin. Apheresis 2010. © 2010 Wiley‐Liss, Inc.