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Plasmapheresis in acute disseminated encephalomyelitis
Author(s) -
Lin ChinHsien,
Jeng JiannShing,
Yip PingKeung
Publication year - 2004
Publication title -
journal of clinical apheresis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.697
H-Index - 46
eISSN - 1098-1101
pISSN - 0733-2459
DOI - 10.1002/jca.20022
Subject(s) - plasmapheresis , acute disseminated encephalomyelitis , medicine , encephalomyelitis , corticosteroid , pediatrics , intensive care medicine , surgery , multiple sclerosis , immunology , antibody
High‐dose corticosteroid administration has been regarded as the main therapy for acute disseminated encephalomyelitis (ADEM). However, some patients with ADEM do not respond well to this treatment. We successfully used plasmapheresis to treat 2 patients who had ADEM. We also compared our patients' symptoms and clinical outcomes to those from previous reports. Plasmapheresis may be indicated not only for severe cases that fail to improve after high‐dose corticosteroid treatment but also for first‐line treatment. Additional large, controlled, double‐blinded trials are needed to clarify the role of plasmapheresis in ADEM. J Clin. Apheresis 19:154–159, 2004. © 2004 Wiley‐Liss, Inc.