Premium
Preparation and adsorption characteristic of polymeric microsphere with strong adsorbability for creatinine
Author(s) -
Gao Baojiao,
Yang Ying,
Wang Jian,
Zhang Yan
Publication year - 2008
Publication title -
journal of biochemical and molecular toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.526
H-Index - 58
eISSN - 1099-0461
pISSN - 1095-6670
DOI - 10.1002/jbt.20221
Subject(s) - adsorption , methacrylate , copolymer , chemistry , fourier transform infrared spectroscopy , microsphere , nuclear chemistry , polymer chemistry , chemical engineering , organic chemistry , polymer , engineering
Cross‐linking terpolymer microspheres (HEMA/NVP/MBA; it can also be designated as HEMA/NVP because HEMA and NVP are main components) with an average diameter of 180 µm, were prepared via inverse suspension copolymerization by using 2‐hydroxyethyl methacrylate (HEMA) and N ‐vinylpyrrolidone (NVP) as monomers and N , N ′‐methylene bisacrylamide (MBA) as cross‐linked agent. The microsphere HEMA/NVP was chemically modified with 3,5‐dinitrobenzoyl chloride (DNBC), and the functional microsphere DNBZ‐HEMA/NVP, on which a great number of 3,5‐dinitrobenzoate group (DNBZ) were bound, was obtained. The functional microsphere DNBZ‐HEMA/NVP were characterized with FTIR and the chemical analysis method. The adsorption characteristics and mechanism of the absorption of DNBZ‐HEMA/NVP for creatine was mainly studied. The results of static adsorption experiments show that the functional microsphere DNBZ‐HEMA/NVP has very strong adsorption ability for creatinine, and the saturated adsorption amount is 25 mg/g. The adsorption capacity of the functional microsphere DNBZ‐HEMA/NVP for creatinine is enhanced 20 times as against unmodified microsphere HEMA/NVP. The adsorption capacity is smaller, at lower and higher pH, and has a maximum as pH 8.5. The higher the salinity of the medium, the smaller the adsorption capacity. The adsorption capacity decreases with increasing temperature. The study results show that the adsorption of the microsphere DNBZ‐HEMA/NVP for creatinine is ascribed to a chemical adsorption by driving of electrostatic interaction. © 2008 Wiley Periodicals, Inc. J Biochem Mol Toxicol 22:166–174, 2008; Published online in Wiley InterScience ( www.interscience.wiley.com ). DOI 10.1002/jbt.20221