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Heat shock response: hsp70 in environmental monitoring
Author(s) -
Mukhopadhyay Indranil,
Nazir Aamir,
Saxena D. K.,
Chowdhuri D. Kar
Publication year - 2003
Publication title -
journal of biochemical and molecular toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.526
H-Index - 58
eISSN - 1099-0461
pISSN - 1095-6670
DOI - 10.1002/jbt.10086
Subject(s) - hsp70 , heat shock protein , shock (circulatory) , heat shock , microbiology and biotechnology , in vitro , denaturation (fissile materials) , environmental stress , biology , transgene , in vivo , genetically modified mouse , computational biology , chemistry , biochemistry , genetics , ecology , medicine , gene , nuclear chemistry
Heat shock proteins (Hsps) are a ubiquitous feature of cells in which these proteins cope with stress‐induced denaturation of other proteins. Among the different families of Hsps, the 70 kDa family ( hsp70 ) is the most highly conserved and has been most extensively studied. Apart from their primary role in cellular defense under stress condition, a number of studies in recent years have shown the immense potential of hsp70 in pollution monitoring using even transgenic approach both in vivo and in vitro. This article reviews the recent developments in the widespread application of hsp70 in environmental risk assessment. © 2003 Wiley Periodicals, Inc. J Biochem Mol Toxicol 17:249–254, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/jbt.10086