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Does estimating volumetric bone density of the femoral neck improve the prediction of hip fracture? A prospective study
Author(s) -
Cummings Steven R.,
Marcus Robert,
Palermo Lisa,
Ensrud Kristine E.,
Genant Harry K.
Publication year - 1994
Publication title -
journal of bone and mineral research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.882
H-Index - 241
eISSN - 1523-4681
pISSN - 0884-0431
DOI - 10.1002/jbmr.5650090915
Subject(s) - medicine , femoral neck , bone mineral , hip fracture , bone density , nuclear medicine , orthodontics , radiology , surgery , osteoporosis
Standard projectional bone density of the femoral neck (BMD), defined as bone mineral content divided by the projected area of the neck, predicts hip fractures but may not accurately estimate the true volumetric bone density of the femoral neck. To determine whether an estimate of the volumetric bone density of the neck, “bone mineral apparent density” (BMAD), would be a better predictor of hip fracture, we analyzed dual x‐ray absorptiometry scans obtained prospectively from 7963 older white women, of whom 83 suffered a hip fracture during follow‐up. Both BMD and BMAD were stronger predictors than bone mineral content (BMC) of the femoral neck. However, BMD and BMAD had very similar predictive values for hip fracture: each standard deviation decrease in either BMD or BMAD of the femoral neck increased the age‐adjusted risk of hip fracture 2.6‐ to 2.7‐fold. We conclude that BMD and BMAD of the femoral neck have a similarly strong predictive value for hip fracture.