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Cross‐sectional and longitudinal study of age‐related phalangeal bone loss in adult females
Author(s) -
Trouerbach W.T.,
VechtHart C.M.,
Collette H.J.A.,
Slooter G.D.,
Zwamborn A.W.,
Schmitz P.I.M.
Publication year - 1993
Publication title -
journal of bone and mineral research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.882
H-Index - 241
eISSN - 1523-4681
pISSN - 0884-0431
DOI - 10.1002/jbmr.5650080606
Subject(s) - medicine , osteoporosis , bone mass , menopause , postmenopausal osteoporosis , peak bone mass , longitudinal study , dentistry , physiology , bone mineral , pathology
To establish a comprehensive model for peripheral phalangeal bone loss, bone mass was studied in 1984 and 1989 using quantitative microdensitometry (QMD) in a total of 330 healthy women (age range 43–78.7 years). Bone mass and changes in bone mass were analyzed in relation to age and menopausal status. Ideal and nonideal populations were distinguished to assess the effect of diseases and medication. Both groups showed a decrease in bone mass, which proved to be more dependent on menopausal status than on age. A substantial loss started in the ideal group in the early postmenopausal period and in the nonideal group in the premenopausal period. Because the nonideal group started to lose bone at an earlier stage, the lifetime risk for osteoporosis is higher than in the ideal group.