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Bone mass measurements in the distal forearm using dual‐energy X‐ray absorptiometry and γ‐ray computed tomography: A longitudinal, in vivo comparative study
Author(s) -
Overton Thomas R.,
Wheeler Garry D.
Publication year - 1992
Publication title -
journal of bone and mineral research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.882
H-Index - 241
eISSN - 1523-4681
pISSN - 0884-0431
DOI - 10.1002/jbmr.5650070404
Subject(s) - tomography , dual energy x ray absorptiometry , x ray , forearm , medicine , dual energy , nuclear medicine , computed tomography , in vivo , radiology , anatomy , bone mineral , physics , osteoporosis , pathology , optics , biology , microbiology and biotechnology
Indices of bone mass were measured in 23 volunteers weekly over 14–16 weeks using dual‐energy x‐ray absorptiometry (DEXA) and special‐purpose computed tomography (γ‐CT). In vitro, the precision for both systems was excellent (coefficient of variation < 0.5%). Over 4 months, the precision in vivo (average CV for all subjects) for DEXA measures (BMD, g/cm 2 , and BMC, g/cm) varied between 0.6 and 1.1%; with γ‐CT it varied from 1.1% for TBD (g/cm 3 ) to 2.2% for CBD (g/cm 3 ). Correlation between the indices of bone mass measured using DEXA and γ‐CT at the ultradistal site was moderate, but these indices were not correlated at the distal third site. When BMD and BMC were derived from the CT index IBD, however, the correlation between these γ‐CT indices and the corresponding DEXA indices was high for both ultradistal and proximal radial sites.