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Localization of parathyroid tumors in patients with asymptomatic hyperparathyroidism and no previous surgery
Author(s) -
Doppman John L.,
Miller Donald L.
Publication year - 1991
Publication title -
journal of bone and mineral research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.882
H-Index - 241
eISSN - 1523-4681
pISSN - 0884-0431
DOI - 10.1002/jbmr.5650061431
Subject(s) - medicine , primary hyperparathyroidism , asymptomatic , magnetic resonance imaging , ultrasound , hyperparathyroidism , radiology , scintigraphy , subtraction , thallium , nuclear medicine , surgery , inorganic chemistry , chemistry , mathematics , arithmetic
A number of recently published series were reviewed evaluating noninvasive localizing studies (ultrasound, thallium‐technetium subtraction scintigraphy, computed tomography, and magnetic resonance imaging) in patients with primary hyperparathyroidism and no previous surgery. The average true positive (%) and false positive (%) rates were (1) ultrasound, 66 and 12; (2) Th/Tc scanning 55 and 13; (3) computed tomography, 63 and inadequately documented; (4) magnetic resonance imaging, 75 and 18. The success rate of initial operation in this group of patients is over 90%. There is no evidence that preoperative localizing studies shorten operating time or prevent surgical failures. For these reasons, noninvasive localization studies are not indicated in patients with primary hyperparathyroidism before initial surgery.