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Calcium determination in primary hyperparathyroidism
Author(s) -
Ladenson Jack H.
Publication year - 1991
Publication title -
journal of bone and mineral research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.882
H-Index - 241
eISSN - 1523-4681
pISSN - 0884-0431
DOI - 10.1002/jbmr.5650061411
Subject(s) - calcium , primary hyperparathyroidism , asymptomatic , calcium metabolism , blood calcium , chemistry , hyperparathyroidism , medicine , endocrinology
Calcium is the most closely controlled substance in the blood. The biologic variation of total calcium is ≈ 2% and of the biologically active free (ionized, ionic) calcium only 1%. (1–3) Thus, the monitoring of calcium in blood requires analytic procedures of high precision and accuracy. For patients with asymptomatic primary hyperparathyroidism, calcium monitoring involves the measurement of total calcium and free calcium. This review first considers the measurement of total calcium and then free calcium.