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The impact of menopausal age on future fragility fracture risk
Author(s) -
Gärdsell Per,
Johnell Olof,
Nilsson Bo E.
Publication year - 1991
Publication title -
journal of bone and mineral research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.882
H-Index - 241
eISSN - 1523-4681
pISSN - 0884-0431
DOI - 10.1002/jbmr.5650060502
Subject(s) - quartile , menopause , fragility , medicine , fragility fracture , postmenopausal women , osteoporosis , dentistry , confidence interval , bone mineral , chemistry
Altogether 733 postmenopausal women were interviewed with regard to their age at menopause. Subsequent fragility fractures over an 11 year period were recorded. Fragility fractures had occurred in 212 women. These women had an earlier menopause, but the deviation from the nonfracture group was significant only in those who were <70 years at the beginning of the fracture catchment period. Women 50–69 years of age, in the lowest quartile of menopausal age, sustained 50% more fragility fractures than those in the highest quartile. In older women menopausal age does not predict fragility fractures. Women <70 with an early menopause had a significantly lower initial bone mass.