Premium
One‐component waterborne in vivo cross‐linkable polysiloxane coatings for artificial skin
Author(s) -
Li Ping,
Zhang Ailing,
Zhou Shuxue
Publication year - 2020
Publication title -
journal of biomedical materials research part b: applied biomaterials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.665
H-Index - 108
eISSN - 1552-4981
pISSN - 1552-4973
DOI - 10.1002/jbm.b.34517
Subject(s) - materials science , emulsion , coating , solvent , silicone , hydrosilylation , chemical engineering , catalysis , curing (chemistry) , composite material , organic chemistry , chemistry , engineering
Polysiloxane‐based artificial skins are able to emulate the mechanical and barrier performance of human skin. However, they are usually fabricated in vitro , restricting their diverse applications on human body. Herein, we presented one‐component waterborne cross‐linkable polysiloxane coatings prepared from emulsified vinyl dimethicone, emulsified hydrogen dimethicone, and Karstedt catalyst capsules that were first synthesized by solvent evaporation method. The coating had good storage stability and meanwhile could form an elastic film quickly through merging of silicone oil droplets and subsequent hydrosilylation reaction. It was found that the mass ratio of vinyl dimethicone emulsion/hydrogen dimethicone emulsion (V/H), and the dosage of Karstedt catalyst capsules (K/(V + H)) were critical to the curing time, morphology, and mechanical properties of the coatings. With appropriate values of V/H and K/(V + H), the polysiloxane film had the mechanical performance comparable to that from solvent‐based one. The coating could be topically applied to human skin in vivo and in situ turned into an elastic, invisible thin film with good water resistance. In contrast to those reported polysiloxane materials, the one‐component waterborne polysiloxane coating was nontoxic and convenient for in vivo application on human body, making it be a promising candidate as artificial skin in the fields of cosmetics, medical treatment, and E‐skin.