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Development of a ubiquitously transferrable silver‐nanoparticle‐loaded polymer nanosheet as an antimicrobial coating
Author(s) -
Ito Keisuke,
Saito Akihiro,
Fujie Toshinori,
Miyazaki Hiromi,
Kinoshita Manabu,
Saitoh Daizoh,
Ohtsubo Shinya,
Takeoka Shinji
Publication year - 2016
Publication title -
journal of biomedical materials research part b: applied biomaterials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.665
H-Index - 108
eISSN - 1552-4981
pISSN - 1552-4973
DOI - 10.1002/jbm.b.33429
Subject(s) - nanosheet , materials science , coating , nanotechnology , silver nanoparticle , chitosan , adhesive , nanoparticle , antimicrobial , polymer , layer (electronics) , chemical engineering , composite material , chemistry , organic chemistry , engineering
Ultra‐thin polymer films (nanosheets) fabricated by a layer‐by‐layer (LbL) method possess unique properties such as high flexibility, adhesive strength, and transparency, and can be peeled off from a substrate and attached to various surfaces via a water‐soluble supporting film. Therefore, flexible and transferrable LbL nanosheets are convenient tools as coating materials. Here, we fabricated a novel antimicrobial coating material by embedding silver nanoparticles (AgNPs) in an LbL nanosheet composed of layers of chitosan and sodium alginate (Ag‐LbL nanosheet) by means of a photo‐reduction method. Optimizing the amount of irradiated energy applied led to robust antimicrobial efficacy against methicillin‐resistant Staphylococcus aureus (MRSA), sufficient to meet ISO standards (ISO 22196), while maintaining the flexibility and adhesive potency of the LbL nanosheet. Thus, the Ag‐LbL nanosheet is a promising coating material that can provide antimicrobial efficacy to various surfaces. © 2015 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 104B: 585–593, 2016.