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High vitamin E content, impact resistant UHMWPE blend without loss of wear resistance
Author(s) -
Oral Ebru,
Neils Andrew,
Muratoglu Orhun K.
Publication year - 2015
Publication title -
journal of biomedical materials research part b: applied biomaterials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.665
H-Index - 108
eISSN - 1552-4981
pISSN - 1552-4973
DOI - 10.1002/jbm.b.33256
Subject(s) - materials science , vitamin e , composite material , limiting , irradiation , implant , penetration (warfare) , polyethylene , wear resistance , antioxidant , surgery , organic chemistry , chemistry , medicine , mechanical engineering , physics , operations research , nuclear physics , engineering
Antioxidant stabilization of radiation cross‐linked ultrahigh molecular weight polyethylene (UHMWPE) has been introduced to improve the oxidative stability of total joint implant bearing surfaces. Blending of antioxidants (most commonly vitamin E) with UHMWPE resin powder followed by consolidation and uniform radiation cross‐linking is currently available for use in both total hips and total knees. It was previously shown that the fatigue resistance of vitamin E‐blended and irradiated UHMWPEs could be further improved by spatially manipulating the vitamin E concentration throughout the implant and limiting cross‐linking to the surface of the implant where it is necessary for wear resistance. This was possible by designing a low concentration of vitamin E on the surface and higher concentration in the bulk of the implant because cross‐linking is hindered in UHMWPE as a function of increasing vitamin E concentration. In this study, we hypothesized that such a surface cross‐linked UHMWPE with low wear rate and high fatigue strength could be obtained by limiting the penetration of radiation into UHMWPE with uniform vitamin E concentration. Our hypothesis tested positive; we were able to obtain control of the surface cross‐linked region by manipulating the energy of the irradiation, resulting in extremely low wear, and high impact strength. In addition, we discussed alternatives of improving the oxidation resistance of such a material by using additional vitamin E reservoirs. These results are significant because this material may allow increased use of antioxidant‐stabilized, cross‐linked UHMWPEs in high stress applications and in more active patients. © 2014 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 103B: 790–797, 2015.