Premium
Mechanical attachment of soft tissue to dental and maxillofacial implants with mesh structures: An experiment in percutaneous model
Author(s) -
Asoda Seiji,
Arita Takayuki,
Takakuda Kazuo
Publication year - 2013
Publication title -
journal of biomedical materials research part b: applied biomaterials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.665
H-Index - 108
eISSN - 1552-4981
pISSN - 1552-4973
DOI - 10.1002/jbm.b.32855
Subject(s) - materials science , titanium , soft tissue , implant , biomedical engineering , connective tissue , biomaterial , dentistry , percutaneous , surgery , medicine , pathology , metallurgy , nanotechnology
Soft tissue attachment is a major concern for the improved design of dental and maxillofacial implants. This study evaluated the efficacy of mesh structures for soft tissue attachment in a rat percutaneous model. Four kinds of implant specimens were prepared — TI implants made of titanium cylinders, HA implants of hydroxyapatite‐coated titanium, TI‐Mesh implants with a titanium mesh covering a groove machined around a titanium cylinder, and similar HA‐Mesh implants with a hydroxyapatite‐coated mesh. These specimens were implanted percutaneously into the skin tissue of rats. The detachments of the implants were examined during the experimental period of 4 weeks. Survived implants were subjected to mechanical tests for the attachment strength and histological examinations. TI and HA implants demonstrated 0% of survival rates, while TI‐Mesh and HA‐Mesh showed significantly higher rates of 93.3% and 100% respectively. The attachment strengths were 159 ± 47 kPa in the TI‐Mesh and 135 ± 16 kPa in the HA‐Mesh. Histological observations revealed that collagen fibers originating from surrounding subcutaneous tissues were anchored to the mesh structures of the TI‐ and HA‐Mesh implants. The results demonstrated the efficacy of the mesh structures for the attachment of soft connective tissues to implants. © 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2013.