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Calcium phosphate bioceramics fabricated from extracted human teeth for tooth tissue engineering
Author(s) -
Lim KiTaek,
Suh Je Duck,
Kim Jangho,
Choung PillHoon,
Chung Jong Hoon
Publication year - 2011
Publication title -
journal of biomedical materials research part b: applied biomaterials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.665
H-Index - 108
eISSN - 1552-4981
pISSN - 1552-4973
DOI - 10.1002/jbm.b.31912
Subject(s) - bioceramic , materials science , fourier transform infrared spectroscopy , thermogravimetric analysis , biocompatibility , human tooth , thermal analysis , scanning electron microscope , differential thermal analysis , biomaterial , nuclear chemistry , biomedical engineering , chemical engineering , composite material , metallurgy , chemistry , nanotechnology , diffraction , thermal , enamel paint , medicine , physics , optics , meteorology , engineering
Bioceramic tooth powders were prepared via heat treatment of extracted human teeth using sintering temperatures between 600°C and 1200°C, and their properties were investigated for potential tooth tissue engineering. The sintered human tooth powders were characterized using thermal analysis (thermogravimetric analysis (TG) and differential thermal analysis (DTA)), field emission scanning electron microscopy, X‐ray diffraction, energy dispersive X‐ray spectroscopy, and Fourier transformed infrared (FTIR) spectroscopy. Additionally, the phase constitutions and chemical homogeneities of the composite samples were examined using a quantitative chemical analysis with inductively coupled plasma spectroscopy. The results revealed that the annealing process produced useful hydroxyapatite‐based bioceramic biomaterials when annealed above 1000°C. The FTIR spectra and the TG/DTA thermograms of the tooth powders indicated the presence of organic compounds, which were completely removed after annealing at temperatures above 1000°C. The tooth powders annealed between 1000°C and 1200°C had good characteristics as bioceramic biomaterials. Furthermore, the biocompatibility of each tooth powder was evaluated using in vitro and in vivo techniques; our results indicate that the prepared human tooth powders have great potential for tooth tissue engineering applications. © 2011 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2011.