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3D collagen scaffolds coated with multiwalled carbon nanotubes: Initial cell attachment to internal surface
Author(s) -
Hirata Eri,
Uo Motohiro,
Nodasaka Yoshinobu,
Takita Hiroko,
Ushijima Natsumi,
Akasaka Tsukasa,
Watari Fumio,
Yokoyama Atsuro
Publication year - 2010
Publication title -
journal of biomedical materials research part b: applied biomaterials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.665
H-Index - 108
eISSN - 1552-4981
pISSN - 1552-4973
DOI - 10.1002/jbm.b.31613
Subject(s) - materials science , sponge , adhesion , scaffold , cell adhesion , coating , carbon nanotube , composite material , nanotube , nanotechnology , biomedical engineering , medicine , botany , biology
The cell adhesion in a multiwalled carbon nanotube‐coated collagen sponge (MWCNT‐coated sponge) was investigated. Immediately after seeding, the cells adhered to the inner surface of the MWCNT‐coated sponge and a significantly larger number of cells were observed there than for a pure collagen sponge used as control. On the MWCNT‐coated sponge, the cells appeared favorable adhesion and spread in the early stages in the center part of the sponge which cells rarely attached without MWCNT‐coating. It was suggested that the physical structure of MWCNTs was effective for initial adhesion of cells from the result of serum‐free culture. MWCNT‐coating makes the material a suitable three‐dimensional scaffold for cell culturing, as opposed to other scaffold systems where such an effect is not seen. © 2010 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2010