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Interaction of endothelial cells with methacrylic terpolymer biomaterials
Author(s) -
Heath Daniel E.,
Cooper Stuart L.
Publication year - 2010
Publication title -
journal of biomedical materials research part b: applied biomaterials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.665
H-Index - 108
eISSN - 1552-4981
pISSN - 1552-4973
DOI - 10.1002/jbm.b.31514
Subject(s) - biocompatibility , methacrylic acid , copolymer , methacrylate , biomaterial , umbilical vein , materials science , polymer , methyl methacrylate , chemical engineering , polymer chemistry , glass transition , composite material , chemistry , nanotechnology , biochemistry , in vitro , engineering , metallurgy
A biomaterial system with tunable mechanical properties was synthesized through random copolymerization of hexyl methacrylate, methyl methacrylate, and methacrylic acid. The composition, molecular weight, water absorption, glass transition temperature, and tensile properties of the polymer system were characterized, and the biocompatibility of the material was demonstrated by the ability of human umbilical vein endothelial cells to adhere, proliferate, and spread on the polymer surface. No difference was observed in the behavior of the endothelial cells on the materials regardless of material stiffness. © 2009 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2010