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Biological and antibacterial properties of plasma sprayed wollastonite/silver coatings
Author(s) -
Li Baoe,
Liu Xuanyong,
Cao Cong,
Dong Yuqi,
Ding Chuanxian
Publication year - 2009
Publication title -
journal of biomedical materials research part b: applied biomaterials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.665
H-Index - 108
eISSN - 1552-4981
pISSN - 1552-4973
DOI - 10.1002/jbm.b.31434
Subject(s) - wollastonite , materials science , coating , simulated body fluid , apatite , antibacterial activity , scanning electron microscope , nuclear chemistry , surface modification , silver nitrate , chemical engineering , composite material , chemistry , bacteria , organic chemistry , raw material , biology , engineering , genetics
In this work, plasma sprayed wollastonite/silver coatings were prepared to obtain an implant material having excellent bioactivity, cytocompatibility as well as antibacterial property. The surface characteristics of wollastonite/silver coating were investigated by scanning electron microscopy, energy dispersive spectrometer, atomic absorbance spectroscope and x‐ray diffraction. The bioactivity was examined by simulated body fluid soaking test. The antibacterial activity against Escherichia coli was examined by bacterial counting method. And the cytocompatibility and in vitro osteotoxicity was evaluated by alamarBlue™ Assay using MG‐63 osteoblasts. The results showed that silver existed in the wollastonite coating homogeneously as silver oxide and metal silver, which ensured a sustained release of silver for 28 days in deionized water. The loaded silver showed strong inhibition against the growth of Escherichia coli , however exhibited no osteotoxicity. Although the wollastonite/silver coating can not induce apatite formation as quickly as the wollastonite coating did in simulated body fluid, it still exhibited good bioactivity. Therefore, the plasma sprayed wollastonite/silver coating is a promising implant material to be applied in surgery, reducing postoperative infections. © 2009 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 2009