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In situ preparation and characterization of a novel gelatin/poly( D , L ‐lactide)/hydroxyapatite nanocomposite
Author(s) -
Zheng Xiaotong,
Zhou Shaobing,
Xiao Yu,
Yu Xiongjun,
Feng Bo
Publication year - 2009
Publication title -
journal of biomedical materials research part b: applied biomaterials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.665
H-Index - 108
eISSN - 1552-4981
pISSN - 1552-4973
DOI - 10.1002/jbm.b.31388
Subject(s) - nanocomposite , nanofiber , materials science , fourier transform infrared spectroscopy , gelatin , chemical engineering , scanning electron microscope , transmission electron microscopy , polymer , nanoparticle , polymer chemistry , composite material , nanotechnology , chemistry , organic chemistry , engineering
A novel biodegradable polymer–ceramic nanocomposite was prepared using the in situ preparation method, which consisted of gelatin (gel), poly( D , L ‐lactide) (PDLLA), and hydroxyapatite (HA) nanofibers. In this article, the HA nanofibers with length/diameter (L/D) ratio of 19.8 in gel/PDLLA/HA nanocomposites were synthesized and precipitated in polymeric matrix by one‐step hydrothermal mineralization. The crystalline phases, structural morphology, mechanical characterization, and chemical interaction of gel/PDLLA/HA nanocomposites were investigated by X‐ray diffraction, transmission electron microscopy, scanning electron microscopy, energy dispersive X‐ray spectroscopy, mechanical test, and Fourier transform infrared spectroscopy. The results showed that the crystalline HA nanofibers were uniformly mineralized in gel and PDLLA matrix and the interaction between Ca 2+ in HA (nanofibers and negative‐charged functional groups in gel and PDLLA molecular chains was formed. Thus, the schematic model of two polymeric chains bridged by inorganic nanofibers was designed on the basis of the experimental results. Moreover, it can clearly explain why the mechanical properties of gel/PDLLA/HA nanocomposites turned strong. © 2009 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2009