Premium
Characteristics of Hylamer polyethylene particles isolated from peri‐prosthetic tissues of failed cemented total hip arthroplasties
Author(s) -
Iwakiri Kentaro,
Iwaki Hiroyoshi,
Kobayashi Akio,
Minoda Yukihide,
Kagiyama Hiroshi,
Kadoya Yoshinori,
Takaoka Kunio
Publication year - 2008
Publication title -
journal of biomedical materials research part b: applied biomaterials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.665
H-Index - 108
eISSN - 1552-4981
pISSN - 1552-4973
DOI - 10.1002/jbm.b.30924
Subject(s) - polyethylene , osteolysis , total hip arthroplasty , cross linked polyethylene , scanning electron microscope , materials science , total hip replacement , prosthesis , composite material , particle size , particle (ecology) , dentistry , biomedical engineering , medicine , surgery , chemistry , oceanography , geology
Polyethylene wear particles are one of the most important factors affecting the results of total hip arthroplasty. Hylamer, a highly crystalized ultra‐high‐molecular‐weight polyethylene, has been used in total hip arthroplasty for wear reduction, but has exhibited high wear rate and excessive osteolysis. The aim of the present study was to examine Hylamer wear particles in peri‐prosthetic tissues with osteolysis obtained from two cases of failed cemented total hip arthroplasty at 8 and 6 years after operation. Polyethylene particles were isolated, and examined using a scanning electron microscope and image analyzer. Total numbers of Hylamer polyethylene particles in the two cases were 5.6 × 10 9 and 8.0 × 10 9 g −1 . Particle sizes (in equivalent circle diameter) for the two cases were 1.07 ± 0.06 μm and 1.16 ± 0.05 μm, and particle shapes (roundness) were 3.05 ± 0.22 and 3.76 ± 0.28. The Hylamer polyethylene particles were larger in size and more elongated and their number was larger, compared with the corresponding reported values for particles generated from conventional polyethylene. This increase in particle number and elongation may lead to early osteolysis in total hip arthroplasty with Hylamer. © 2007 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2008