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Collagen‐apatite nanocomposite membranes for guided bone regeneration
Author(s) -
Song JuHa,
Kim HyounEe,
Kim HaeWon
Publication year - 2007
Publication title -
journal of biomedical materials research part b: applied biomaterials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.665
H-Index - 108
eISSN - 1552-4981
pISSN - 1552-4973
DOI - 10.1002/jbm.b.30790
Subject(s) - nanocomposite , biomaterial , apatite , materials science , membrane , regeneration (biology) , chemical engineering , biomedical engineering , composite material , nanotechnology , chemistry , medicine , biochemistry , engineering , biology , microbiology and biotechnology
Collagen‐apatite nanocomposite is regarded as a potential biomaterial because of its composition and structure, which are similar to those of human hard tissues. However, there have been few investigations of its mechanical and biological benefits in direct comparison with a collagen equivalent. Herein, we successfully produced a biomedical membrane made of a nanocomposite, and systemically evaluated the mechanical, chemical, and biological properties of the nanocomposite in comparison with those of pure collagen. The results showed that significant improvements were achieved by the nanocomposite approach, particularly in terms of the mechanical strength and chemical stability. The present findings point to the potential usefulness of the collagen‐apatite nanocomposite membrane in the field of guided bone regeneration (GBR). © 2007 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2007