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Wet chemical silver treatment of endotracheal tubes to produce antibacterial surfaces
Author(s) -
Ramstedt Madeleine,
Houriet Raymond,
Mossialos Dimitris,
Haas Dieter,
Mathieu Hans Jörg
Publication year - 2007
Publication title -
journal of biomedical materials research part b: applied biomaterials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.665
H-Index - 108
eISSN - 1552-4981
pISSN - 1552-4973
DOI - 10.1002/jbm.b.30781
Subject(s) - x ray photoelectron spectroscopy , fourier transform infrared spectroscopy , nuclear chemistry , scanning electron microscope , bacterial growth , leaching (pedology) , silver chloride , materials science , chloride , surface modification , bacteria , chemistry , metallurgy , chemical engineering , composite material , environmental science , electrode , biology , soil water , soil science , engineering , genetics
Mechanically ventilated patients in hospitals are subjected to an increased risk of acquiring nosocomial pneumonia that sometimes has a lethal outcome. One way to minimize the risk could be to make the surfaces on endotracheal tubes antibacterial. In this study, bacterial growth was inhibited or completely prevented by silver ions wet chemically and deposited onto the tube surface. Through the wet chemical treatment developed here, a surface precipitate was formed containing silver chloride and a silver stearate salt. The identity and morphology of the surface precipitate was studied using x‐ray photoelectron spectroscopy, Fourier transform infrared spectroscopy, scanning electron microscopy, and x‐ray powder diffraction. Leaching of silver ions into solution was examined, and bacterial growth on the treated surfaces was assayed using Pseudomonas aeruginosa wild type (PAO1) bacteria. Furthermore, the minimum inhibitory concentration of silver ions was determined in liquid‐ and solid‐rich growth medium as 23 and 18 μM, respectively, for P. aeruginosa . © 2007 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2007