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Mechanical properties and biological behavior of carbon nanotube/polycarbosilane composites for implant materials
Author(s) -
Wang Wei,
Watari Fumio,
Omori Mamoru,
Liao Susan,
Zhu Yuhe,
Yokoyama Atsuro,
Uo Motohiro,
Kimura Hisamichi,
Ohkubo Akira
Publication year - 2007
Publication title -
journal of biomedical materials research part b: applied biomaterials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.665
H-Index - 108
eISSN - 1552-4981
pISSN - 1552-4973
DOI - 10.1002/jbm.b.30724
Subject(s) - materials science , spark plasma sintering , composite material , carbon nanotube , composite number , bone tissue , implant , hard tissue , nanotube , sintering , biomedical engineering , dentistry , surgery , medicine
Multiwalled carbon nanotube/polycarbosilane (MWCNT/PCS) composites were fabricated by the spark plasma sintering (SPS) method. The MWCNT/PCS composites consisted of MWCNTs and nanosized SiC particles pyrolyzed from PCS and possessing good mechanical properties for bone tissue repair or dental implantation. The MWCNT/PCS composites were implanted in the subcutaneous tissue and femur of rats at 1 and 4 weeks after implantation. Histological investigations showed that there was little inflammatory response in the subcutaneous tissue, and newly formed bone tissue was observed in the femur. These results indicated that the MWCNT/PCS composite had little prophlogistic effect and good osteoconductivity. The study suggested the possibility that the MWCNT/PCS composite could be a candidate bone‐substitute and dental‐implant material in the future. © 2006 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 2006.