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Hemocompatibility of low‐friction boron–carbon–nitrogen containing coatings
Author(s) -
Maitz M. F.,
Gago R.,
Abendroth B.,
Camero M.,
Caretti I.,
Kreissig U.
Publication year - 2006
Publication title -
journal of biomedical materials research part b: applied biomaterials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.665
H-Index - 108
eISSN - 1552-4981
pISSN - 1552-4973
DOI - 10.1002/jbm.b.30435
Subject(s) - materials science , crystallinity , adsorption , boron nitride , carbon fibers , ferrous , tribology , boron , chemical engineering , amorphous carbon , composite material , graphite , amorphous solid , graphene , platelet activation , surface energy , nanotechnology , metallurgy , platelet , composite number , chemistry , organic chemistry , immunology , engineering , biology
Mechanical heart valves are exposed to extreme mechanical demands, which require a surface showing not only nonhaemostatic properties, but also wear resistance and low friction. As alternative to different forms of amorphous carbon (a‐C), so‐called diamond‐like carbon (DLC), the suitability of boron carbonitride (BCN) coatings is tested here for hemocompatible coatings. They have similar mechanical properties like a‐C surfaces, but superior chemical stability at ferrous substrates or counterparts. BCN films with different nitrogen content were compared with hydrogenated a‐C films regarding their mechanical properties, surface energy, adsorption of albumin and fibrinogen, blood platelet adherence, and activation of the contact system of the clotting cascade and kinin system. Similar mechanical properties and biological response have been found in the BCN films with respect to a‐C, indicating the potential of these coatings for biomedical applications. The increase in the crystallinity and tribological properties of the BCN samples with a higher incorporation of N was also followed by a lower protein adsorption and low activation of the contact system, but an increased adherence of thrombocytes. © 2005 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2006