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Sol‐gel preparation and in vitro test of fluorapatite/hydroxyapatite films
Author(s) -
Cheng Kui,
Weng Wenjian,
Qu Haibo,
Du Piyi,
Shen Ge,
Han Gaorong,
Yang Juan,
Ferreira J. M. F.
Publication year - 2003
Publication title -
journal of biomedical materials research part b: applied biomaterials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.665
H-Index - 108
eISSN - 1552-4981
pISSN - 1552-4973
DOI - 10.1002/jbm.b.20027
Subject(s) - fluorapatite , dissolution , solubility , materials science , substrate (aquarium) , tris , chemical engineering , titanium , sol gel , nuclear chemistry , deposition (geology) , phosphate buffered saline , chemistry , mineralogy , apatite , chromatography , nanotechnology , metallurgy , organic chemistry , biochemistry , paleontology , oceanography , sediment , engineering , biology , geology
Fluorapatite/hydroxyapatite (FA/HA) films have been demonstrated to be a good alternative to pure hydroxyapatite (HA) ones in medical applications because of their bioactivity and relatively low solubility. In this study, Ca(NO 3 ) 2 , P 2 O 5 , and HPF 6 were used to prepare FA/HA films on Ti6Al4V substrate with the use of a sol‐gel method. The F contents in the films could be tailored by adjusting the amount of HPF 6 added. The in vitro evaluation of the films was carried out in both SBF9# solution and TRIS buffer solution. The films with appropriate F contents showed a better ability to induce calcium phosphate deposition on their surfaces than either pure HA film and FA/HA films with even higher F content, as well as smaller dissolution amounts than HA film in TRIS buffer solution. Hence, the FA/HA films obtained in this work integrate both good bioactivity and stability, and could be a better choice for bioactive film on titanium alloys to produce high‐quality implants. © 2003 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 69B: 33–37, 2004