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Evaluation of a new CPC‐to‐gauge bonding technique with the use of in vitro fluid flow
Author(s) -
Fernandez Mark M.,
Szivek John A.,
Margolis David S.
Publication year - 2003
Publication title -
journal of biomedical materials research part b: applied biomaterials
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.665
H-Index - 108
eISSN - 1552-4981
pISSN - 1552-4973
DOI - 10.1002/jbm.b.10040
Subject(s) - polyimide , composite material , materials science , epoxy , polysulfone , strain gauge , shear strength (soil) , ceramic , biomedical engineering , layer (electronics) , polymer , medicine , environmental science , soil science , soil water
Strain gauging enables the measurement of bone deformation during physical activity, leading to a better understanding of the physiological effects of loading on bone growth and remodeling. Development of a technology that will withstand long‐term in vivo exposure and bond securely to bone is imperative for accurate, consistent measurement collection. Polysulfone is currently used to attach calcium‐phosphate ceramic (CPC) particles, which promote bone‐to‐gauge bonding, to polyimide‐backed strain gauges. This study evaluated the use of an implant‐grade epoxy as an alternative CPC–polyimide adhesive. Polyimide–epoxy–CPC interfaces were loaded to failure and shear strengths calculated. In vitro studies providing a constant flow of medium over test specimens were designed, and long‐term in vitro fluid exposure studies of the epoxy's shear strength were conducted. Average shear strength of polysulfone‐polyimide interfaces were reported to be 7 MPa.11 The average shear strength of the epoxy‐polyimide interface before long‐term in vitro exposure was 17 MPa, which is stronger than the shear strength of the bone–CPC interface.12 The strength of the epoxy–polyimide interface decreased to 6.8 MPa after 24 weeks in vitro and 3 MPa after 24 weeks in vivo . © 2003 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 66B: 514–519, 2003