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Processing and strengthening of 58S bioactive glass‐infiltrated titania scaffolds
Author(s) -
MesquitaGuimarães J.,
Leite M. A.,
Souza J. C. M.,
Henriques B.,
Silva F. S.,
Hotza D.,
Boccaccini A. R.,
Fredel M. C.
Publication year - 2017
Publication title -
journal of biomedical materials research part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.849
H-Index - 150
eISSN - 1552-4965
pISSN - 1549-3296
DOI - 10.1002/jbm.a.35937
Subject(s) - materials science , composite material , porosity , ceramic , polyurethane , compressive strength , sponge , zeta potential , interconnectivity , rheology , suspension (topology) , nanotechnology , nanoparticle , pure mathematics , biology , botany , mathematics , artificial intelligence , homotopy , computer science
In this work, TiO 2 ceramic scaffolds were fabricated by the replica method using polyurethane (PU) sponges. Suspensions with high solid content were used to achieve scaffolds with improved mechanical behavior. TiO 2 ceramic suspensions were optimized by rheological studies using different additives. It was found that the composition with 0.5 wt % Darvan enhanced the covering of the sponge struts. PU sponges of 45 to 80 ppi (pore per inch) were well coated without clogging pores. A thermal treatment with varying holding times, temperatures and heating rates was adjusted. The influence of different pore sizes on mechanical strength was evaluated. It was possible to obtain TiO 2 scaffolds with 90% porosity and high pore interconnectivity, having compressive strength exceeding 0.6 MPa. TiO 2 scaffolds were filled up with a 58S bioactive glass suspension to impart bioactive character to the scaffolds. These hybrid structures presented mechanical strengthening of about 26–213% depending on their sponge porosity. The prediction for cells viability via zeta potential measures indicated that this hybrid material is very promising for scaffold application with −19 to −25 mV between pH of 7.35–7.45. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 105A: 590–600, 2017.