Premium
A biomechanical evaluation of CNT ‐grown bone
Author(s) -
PourAkbar Saffar Kaveh,
Sudak Leszek J.,
Federico Salvatore
Publication year - 2016
Publication title -
journal of biomedical materials research part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.849
H-Index - 150
eISSN - 1552-4965
pISSN - 1549-3296
DOI - 10.1002/jbm.a.35582
Subject(s) - materials science , mechanical strength , carbon nanotube , durability , bone tissue , process (computing) , bone remodeling , regeneration (biology) , composite number , artificial bone , composite material , biomedical engineering , computer science , microbiology and biotechnology , engineering , biology , genetics , operating system
Beside their biochemical properties, the exceptional mechanical characteristics of carbon nanotubes (CNTs) suggested growing a reinforced composite material very similar to natural bone in structure and chemical composition, but significantly stronger and stiffer. This is where biomechanical considerations portray themselves to justify the need for further investigations, in order to verify the applicability of CNTs as scaffolds that may ease bone regeneration and simultaneously raise its mechanical strength and durability. This research, using several modeling approaches, attempts to look at some of the mechanical changes likely to take place in the promised artificial tissue, while considering the relationships between mechanical and living functions of bone, particularly the remodeling process. Results suggest that notwithstanding the significant improvements induced to the mechanical behavior of the artificial tissue, applications of such stiff inclusions as CNTs in reinforcing the material of bone may detrimentally change the thresholds of mechanical stimuli that are essential for the initiation and resumption of the bone remodeling process. © 2015 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 104A: 465–475, 2016.