Premium
The application of nanomaterials in controlled drug delivery for bone regeneration
Author(s) -
Shi Shuo,
Jiang Wenbao,
Zhao Tianxiao,
Aifantis Katerina E.,
Wang Hui,
Lin Lei,
Fan Yubo,
Feng Qingling,
Cui Fuzhai,
Li Xiaoming
Publication year - 2015
Publication title -
journal of biomedical materials research part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.849
H-Index - 150
eISSN - 1552-4965
pISSN - 1549-3296
DOI - 10.1002/jbm.a.35522
Subject(s) - drug delivery , regeneration (biology) , nanomaterials , materials science , nanotechnology , drug , bone tissue , biomedical engineering , pharmacology , medicine , biology , microbiology and biotechnology
Bone regeneration is a complicated process that involves a series of biological events, such as cellular recruitment, proliferation and differentiation, and so forth, which have been found to be significantly affected by controlled drug delivery. Recently, a lot of research studies have been launched on the application of nanomaterials in controlled drug delivery for bone regeneration. In this article, the latest research progress in this area regarding the use of bioceramics‐based, polymer‐based, metallic oxide‐based and other types of nanomaterials in controlled drug delivery for bone regeneration are reviewed and discussed, which indicates that the controlling drug delivery with nanomaterials should be a very promising treatment in orthopedics. Furthermore, some new challenges about the future research on the application of nanomaterials in controlled drug delivery for bone regeneration are described in the conclusion and perspectives part. © 2015 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 103A: 3978–3992, 2015.