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Osseointegration of atmospheric plasma‐sprayed titanium implants: Influence of the native oxide layer
Author(s) -
Cunha Alexandre,
Renz Renata Pedrolli,
Blando Eduardo,
Oliveira Rogério Belle,
Hübler Roberto
Publication year - 2014
Publication title -
journal of biomedical materials research part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.849
H-Index - 150
eISSN - 1552-4965
pISSN - 1549-3296
DOI - 10.1002/jbm.a.34667
Subject(s) - osseointegration , materials science , titanium , biomedical engineering , layer (electronics) , implant , scanning electron microscope , porosity , titanium oxide , bone tissue , dentistry , composite material , chemical engineering , metallurgy , medicine , surgery , engineering
The aim of this study was to evaluate in vivo the influence of the native oxide layer on osseointegration and new bone formation on the surface of atmospheric plasma‐sprayed porous titanium coatings. Porous titanium coatings were deposited on all implant surfaces, and half of the samples were subsequently submitted to oxide layer removal treatment. Samples were implanted onto the cortical bone of sheep (tibia) and evaluated at 30 and 60 days. Implants were removed en bloc and the attachment of bone to implants was examined by tensile pull‐out test (osseointegration assessment), light microscopy, scanning electron microscopy (histological analysis), and instrumented hardness tests (mechanical properties of mature and newly formed bone tissue). Coatings submitted to oxide layer treatment presented higher osseointegration values at both healing periods and showed more mature and mineralized bone tissue when compared with nontreated coatings. Our findings showed that the use of acid‐etching in association with atmospheric plasma spraying techniques improves osseointegration of titanium implants. © 2013 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 102A: 30–36, 2014.