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Bacterial adhesion on biomedical surfaces covered by micrometric silver Islands
Author(s) -
PérezTanoira R.,
PérezJorge C.,
Endrino J. L.,
GómezBarrena E.,
Horwat D.,
Pierson J. F.,
Esteban J.
Publication year - 2012
Publication title -
journal of biomedical materials research part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.849
H-Index - 150
eISSN - 1552-4965
pISSN - 1549-3296
DOI - 10.1002/jbm.a.34090
Subject(s) - materials science , nanocrystalline material , adhesion , staphylococcus epidermidis , antimicrobial , coating , ternary operation , sputter deposition , metallurgy , staphylococcus aureus , nanotechnology , sputtering , microbiology and biotechnology , thin film , bacteria , composite material , biology , genetics , computer science , programming language
A set of Cu‐Mn‐O and Ag‐Cu‐Mn‐O films were sputter‐deposited onto polished Ti‐6Al‐4V coupons and the microbiological adherence of Staphylococcus sp. was studied in these biomedical surfaces modified by using advanced ternary and quaternary oxides, these latter incorporated micrometric silver islands. Silver is known to have a natural biocidal character and its presence in the surface of Ti‐6Al‐4V forming large micrometric islands. In principle, predicted to enhance the antimicrobial properties of biomedical surfaces. Microbial adhesion tests were performed using collection strains and six clinical Staphylococcus aureus and Staphylococcus epidermidis strains. The adherence study was performed using a previously published protocol by Kinnari et al. Collection strains and clinical strains showed decreased adherence to modified materials; however, only on the clinical strains were there statistically significant differences between Cu‐Mn‐O and Ag‐Cu‐Mn‐O containing silver islands. Nanocrystalline silver dissolves and releases both Ag + and Ag 0 whereas other silver sources release only Ag+. We can conclude that nanocrystalline silver coating, confirmed by XRD, appears to alter the biological properties of the solution, particularly antimicrobial activity. © 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part A, 2012.