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Tailoring nanocrystalline diamond coated on titanium for osteoblast adhesion
Author(s) -
Pareta Rajesh,
Yang Lei,
Kothari Abhishek,
Sirinrath Sirivisoot,
Xiao Xingcheng,
Sheldon Brian W.,
Webster Thomas J.
Publication year - 2010
Publication title -
journal of biomedical materials research part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.849
H-Index - 150
eISSN - 1552-4965
pISSN - 1549-3296
DOI - 10.1002/jbm.a.32821
Subject(s) - materials science , diamond , titanium , wetting , chemical vapor deposition , nanoindentation , adhesion , composite material , crystallinity , grain size , osteoblast , chemical engineering , nanotechnology , metallurgy , chemistry , engineering , in vitro , biochemistry
Diamond coatings with superior chemical stability, antiwear, and cytocompatibility properties have been considered for lengthening the lifetime of metallic orthopedic implants for over a decade. In this study, an attempt to tailor the surface properties of diamond films on titanium to promote osteoblast (bone forming cell) adhesion was reported. The surface properties investigated here included the size of diamond surface features, topography, wettability, and surface chemistry, all of which were controlled during microwave plasma enhanced chemical‐vapor‐deposition (MPCVD) processes using CH 4 ‐Ar‐H 2 gas mixtures. The hardness and elastic modulus of the diamond films were also determined. H 2 concentration in the plasma was altered to control the crystallinity, grain size, and topography of the diamond coatings, and specific plasma gases (O 2 and NH 3 ) were introduced to change the surface chemistry of the diamond coatings. To understand the impact of the altered surface properties on osteoblast responses, cell adhesion tests were performed on the various diamond‐coated titanium. The results revealed that nanocrystalline diamond (grain sizes <100 nm) coated titanium dramatically increased surface hardness, and the introduction of O 2 and NH 3 during the MPCVD process promoted osteoblast adhesion on diamond and, thus, should be further studied for improving orthopedic applications. © 2010 Wiley Periodicals, Inc. J Biomed Mater Res Part A, 2010.