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Anti‐inflammatory properties of bioactive titanium metals
Author(s) -
Yang Bangcheng,
Gan Lu,
Qu Yang,
Yue Chongxia
Publication year - 2010
Publication title -
journal of biomedical materials research part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.849
H-Index - 150
eISSN - 1552-4965
pISSN - 1549-3296
DOI - 10.1002/jbm.a.32743
Subject(s) - titanium , materials science , apatite , adhesion , metal , myeloperoxidase , nuclear chemistry , in vivo , chemical engineering , metallurgy , composite material , inflammation , chemistry , biology , engineering , microbiology and biotechnology , immunology
Anti‐inflammatory properties of bioactive titanium metals prepared by anodic oxidation (AO‐Ti) and alkali‐heat (AH‐Ti) treatments were studied by bacterial adhesion test and myeloperoxidase (MPO) activity assay methods. The bioactivities of the metals were also evaluated by apatite formation ability and osteoblasts culture experiments. Both metals could induce apatite formation and support osteoblasts proliferation. At the condition with normal incandescent light shine, both bioactive titanium metals had antibacterial adhesion properties compared with the titanium metal without treatment. The MPO activity assay proved that they both showed anti‐inflammatory properties in vivo . The bioactive AO‐Ti had better anti‐inflammatory properties than the AH‐Ti. It indicated that it is possible to optimize the anti‐inflammatory properties of the bioactive titanium metals by different preparation methods. © 2010 Wiley Periodicals, Inc. J Biomed Mater Res Part A, 2010