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Bacterial adherence to SiO 2 ‐based multifunctional bioceramics
Author(s) -
Kinnari Teemu J.,
Esteban Jaime,
GomezBarrena Enrique,
Zamora Nieves,
FernandezRoblas Ricardo,
Nieto Alejandra,
Doadrio Juan C.,
LópezNoriega Adolfo,
RuizHernández Eduardo,
Arcos Daniel,
ValletRegí María
Publication year - 2008
Publication title -
journal of biomedical materials research part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.849
H-Index - 150
eISSN - 1552-4965
pISSN - 1549-3296
DOI - 10.1002/jbm.a.31943
Subject(s) - materials science , bioceramic , staphylococcus epidermidis , mesoporous material , porosity , staphylococcus aureus , bioactive glass , mesoporous silica , bacteria , chemical engineering , composite material , biology , chemistry , organic chemistry , engineering , genetics , catalysis
The bacterial adherence onto different multifunctional silica‐based bioceramics has been evaluated. Staphylococcus aureus and Staphylococcus epidermidis were chosen, as they cause the majority of the implant‐related infections in this field. Two SiO 2 mesoporous materials (MCM‐41, SBA‐15), an ordered SiO 2 ‐CaO‐P 2 O 5 mesoporous glass (OMG), and a biphasic magnetic bioceramic (BMB), were incubated with S. aureus and S. epidermidis for 90 min, and subsequently sonicated to quantify the number of adhered bacteria on each material. It was found that S. aureus and S. epidermidis (10 8 CFU/mL) adhered significantly less to BMB samples when compared to MCM‐41, SBA‐15, or OMG. However, when the material pores accessible for bacteria in each material were taken into account, the lowest bacterial adherence was found in MCM‐41, and the highest in SBA‐15. The results show that bacterial adherence is higher on mesoporous bioceramics, although this higher microbial attachment is mainly due to the intergranular porosity and grain size morphology rather than to the mesoporous structure. © 2008 Wiley Periodicals, Inc. J Biomed Mater Res, 2009